Active pharmaceutical ingredients - Import export

Ketoprofen is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP, JP monographs. Its CAS-N° reads 22071-15-4. It is used in treatment of arthritis-related inflammatory pains, severe toothaches that result in the inflammation of the gums or nerve pain. Ketoprofen is an acidic, non-opioid analgesic used for pain and inflammation. By inhibiting prostaglandin synthesis at the key enzyme cyclooxygenase, it can be used for acute and chronic pain (e.g. arthrosis and arthritides). Like most active ingredients in its class, it is poorly tolerated by the gastrointestinal tract, a particular side effect is light sensitization. Detailed specification, Certificate of Analysis and samples are available on request.

Doxazosin Mesylate is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads 77883-43-3. It is used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia - BPH. Doxazosin mesylate is a selective α-blocker that selectively binds to α1-receptors, thus dilating peripheral blood vessels. This reduces blood pressure and cholesterol levels of the serum. Detailed specification, Certificate of Analysis and samples are available on request.

5-ALA is an active pharmaceutical ingredient and is produced under cGMP. Values are: * Competitive process * European manufacturer * Registered and approved in EU and US 5-Aminolevulinic acid is an amino acid that belongs to ketocarbonic acids. It is increasingly converted into a red fluorescent molecule in tumor cells. This accumulates in tumor cells about 4 times more than in healthy cells. The substance is a photosensitizer, it can form oxygen radicals with light energy. These radicals destroy the cell, which is why 5-aminoleivulinic acid is used, for example, in skin carcinomas caused by UV radiation.

Trospium chloride is a synthetic API, produced under cGMP. Its quality complies with International Monographs such as European Pharmacopoeia (EP) or US-Pharmacopoeia (USP). CAS number is [10405-02-4]. Trospium chloride is a tropane derivative (3α-nortropanol benzene acid ester) and an anticholinergic agent. This is used to treat urge and reflex incontinence. This is achieved by the competitive blockage of acetylcholine on their receptors. This inhibits the parasympathetic influence, smooth muscles, heart muscle and parts of the peripheral nervous system. Detailed specification, certificates of analysis and samples are available on request.

Doxapram hydrochloride is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP, USP, JP, ANVISA monographs. Its CAS-N° reads 7081-53-0. It is used in intensive care settings to stimulate the respiratory rate in patients with respiratory failure. It may be useful for treating respiratory depression in patients who have taken excessive doses of specific other drugs. Detailed specification, Certificate of Analysis and samples are available on request.

Warfarin Sodium, amorphous is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads [129-06-6]. It is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions. Detailed specification, Certificate of Analysis and samples are available on request. Warfarin sodium is a 4-hydroxycumarin, these are known as vitamin K antagonists. Vitamin K antagonists are anticoagulants that encroach on the blood clotting cascade. Since the substance can have significant fluctuations in its effectiveness, depending on the genotype, the blood clotting levels for dose tuning should be tested regularly.

Crotamiton is an active pharmaceutical ingredient produced under cGMP. * only European manufacturer * competitive process * up-to-date documentation * starting materials sourced from EU (no dependence on China) Crotamitone is an antipruriginosum used to treat burial mites (scabies). It works against the mites themselves, but also against the itching.

Sodium Borohydride is a versatile and selective reducing agent that has a variety of applications in manufacturing of pharmaceutical active ingredients, crop protection agents, aroma compounds and other fine chemicals. Its CAS-N° reads [16940-66-2]. Typical applications are: Reduction of Aldehydes / Acid Chlorides / Anhydrides to primary Alcohols; Reduction of Ketones to secondary Alcohols; Reduction of Imines to Amines; Removing impurities and purification of process streams; Metal ion reduction / Noble metal recovery / Dehalogenations. Sodium Borohydride is due to its reactivity a hazardous compound under dangerous goods regulation which requires specific storage. Our material is usually promptly available from stock for industrial consumers, To influence reactivity and handling comfort the product is available as coarse powder, fine powder and as granules. Detailed specification, material safety data sheet and additional documents are available on request.

Trifluoroacetic acid is a fluoro-organic compound with an interesting list of uses in manufacturing of pharmaceutical active ingredients, crop protection agents, in peptide and in polymer chemistry. Typical applications are: •CF3 building block •Polymerization catalyst •(Trans-)Esterification promoter •Amino acid protection group cleavage (e.g. DIBOC) •Non-aqueous solvent •Hydration of olefins