Active pharmaceutical ingredients - Import export

Pharmaceutical products

Pharmaceutical Products

Active Pharmaceutical Ingredients and Syringes

Pharmaceutical products

Pharmaceutical products

Freeze-drying is an important process for preserving and formulating pharmaceutical and biotechnological active ingredients. If an existing process is changed or transferred, the entire cycle must be modified. We advise on the adaptation of a freeze-drying cycle or scale up. Contact us for an initial discussion! Analysis We analyse existing data, model the process and verify the settings before the conversion. For them, this means: high transfer security, short project times, low overall costs. Adaptation of a freeze drying How do we go about it? For the time being, we analyse all existing data and "build" a model of freeze drying from it. The model is based on the physical principles and the real data of their current plant. Consequently, our predictions and forecasts are accurate. From the model, we obtain the settings for the new freeze-drying process. Before the step into production, these settings are verified with a small system.

The B70V SanitaryPlus food pump is a powerful positive displacement pump for highly sensitive, viscous media with and without fibres or solids up to the limits of flowability. It pumps liquid foodstuffs, active pharmaceutical ingredients and cosmetic products from a wide variety of containers and delivery packs. The pump fulfils the requirements of hygienic design and is certified in accordance with the "3-A Sanitary Standards". With reduction gear for electric motors up to 230 volts * Also available in special immersion depths * Examples of media: liquid foodstuffs and luxury foods, active pharmaceutical ingredients and cosmetic products * Threadless, manually detachable quick connections in the wetted area * Gentle, low-pulsation product conveyance * Certified and approved in accordance with the current "3-A Sanitary Standards for Centrifugal and Positive Rotary Pumps Number 02-10"

The B70V SanitaryPlus food pump is a powerful positive displacement pump for heavy-sensitive, viscous media with and without fiber or solids content up to the limits of flowability. It pumps liquid foodstuffs, active pharmaceutical ingredients and cosmetic products from a wide variety of containers and delivery packages. The pump meets the requirements of hygienic design and is certified according to the "3-A Sanitary Standards". * also available in special immersion depths * equipped as standard with a carrying handle and a Motor * Media examples: liquid foodstuffs and semi-luxury foods, pharmaceutical agents and cosmetic products Features & Benefits * Threadless, manually releasable quick connections in the wetted area * Quick and easy disassembly * Simple and fast cleaning * Gentle, low-pulsation product conveying * Certified and approved according to the current "3-A Sanitary Standards for Centrifugal and Positive Rotary Pumps Number 02-10".

At PACS we are specialists in the supply of raw materials for the pharmaceutical sector such as: APIs, Excipients, vitamins, minerals and natural extracts. Thanks to our vast experience in the industry and our operations in different markets aroud the world, we provide to our clients with an integral service that not only includes the product. We also offer advice on marketing, communications, industry trends, regulatory management and logistics service to destination. Our sales team will be pleased to introduce you the wide range of products available for your company, depending on the application: Anti-Inflamatorys Ani Hyper Lipoprotienemics Anti-Ulcerants Anti-Fungals Anti-Bacterial Anti-Diabetic Anti-Phychotic Anti-Allergic Urogical Drugs Anti-tussive, Expectorarnts Mucohytics

Ketoprofen is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP, JP monographs. Its CAS-N° reads 22071-15-4. It is used in treatment of arthritis-related inflammatory pains, severe toothaches that result in the inflammation of the gums or nerve pain. Ketoprofen is an acidic, non-opioid analgesic used for pain and inflammation. By inhibiting prostaglandin synthesis at the key enzyme cyclooxygenase, it can be used for acute and chronic pain (e.g. arthrosis and arthritides). Like most active ingredients in its class, it is poorly tolerated by the gastrointestinal tract, a particular side effect is light sensitization. Detailed specification, Certificate of Analysis and samples are available on request.

Doxazosin Mesylate is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads 77883-43-3. It is used to treat high blood pressure and urinary retention associated with benign prostatic hyperplasia - BPH. Doxazosin mesylate is a selective α-blocker that selectively binds to α1-receptors, thus dilating peripheral blood vessels. This reduces blood pressure and cholesterol levels of the serum. Detailed specification, Certificate of Analysis and samples are available on request.

5-ALA is an active pharmaceutical ingredient and is produced under cGMP. Values are: * Competitive process * European manufacturer * Registered and approved in EU and US 5-Aminolevulinic acid is an amino acid that belongs to ketocarbonic acids. It is increasingly converted into a red fluorescent molecule in tumor cells. This accumulates in tumor cells about 4 times more than in healthy cells. The substance is a photosensitizer, it can form oxygen radicals with light energy. These radicals destroy the cell, which is why 5-aminoleivulinic acid is used, for example, in skin carcinomas caused by UV radiation.

Trospium chloride is a synthetic API, produced under cGMP. Its quality complies with International Monographs such as European Pharmacopoeia (EP) or US-Pharmacopoeia (USP). CAS number is [10405-02-4]. Trospium chloride is a tropane derivative (3α-nortropanol benzene acid ester) and an anticholinergic agent. This is used to treat urge and reflex incontinence. This is achieved by the competitive blockage of acetylcholine on their receptors. This inhibits the parasympathetic influence, smooth muscles, heart muscle and parts of the peripheral nervous system. Detailed specification, certificates of analysis and samples are available on request.

Doxapram hydrochloride is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP, USP, JP, ANVISA monographs. Its CAS-N° reads 7081-53-0. It is used in intensive care settings to stimulate the respiratory rate in patients with respiratory failure. It may be useful for treating respiratory depression in patients who have taken excessive doses of specific other drugs. Detailed specification, Certificate of Analysis and samples are available on request.

Pipamperone 2HCl is an active pharmaceutical ingredient manufactured following the EU-GMP regulations. We offer the API following EU-GMP (ICH Q7) regulations with an active ASMF. Material is availalbe upon request from stock. The active ingredient is used as an antipsychotic and sedative. It works mainly on the serotonin and dopamine receptors. The sedative effect outweighs that of the antipsychotic. Pipamperone regulates internal restlessness, sleep disturbances, and also weakens arousal conditions, as well as aggressiveness.

Warfarin Sodium, amorphous is a synthetically synthesized Active Pharmaceutical Ingredient, produced under cGMP, compliant with EP monograph. Its CAS-N° reads [129-06-6]. It is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions. Detailed specification, Certificate of Analysis and samples are available on request. Warfarin sodium is a 4-hydroxycumarin, these are known as vitamin K antagonists. Vitamin K antagonists are anticoagulants that encroach on the blood clotting cascade. Since the substance can have significant fluctuations in its effectiveness, depending on the genotype, the blood clotting levels for dose tuning should be tested regularly.

Crotamiton is an active pharmaceutical ingredient produced under cGMP. * only European manufacturer * competitive process * up-to-date documentation * starting materials sourced from EU (no dependence on China) Crotamitone is an antipruriginosum used to treat burial mites (scabies). It works against the mites themselves, but also against the itching.

Trifluoroacetic acid is a fluoro-organic compound with an interesting list of uses in manufacturing of pharmaceutical active ingredients, crop protection agents, in peptide and in polymer chemistry. Typical applications are: •CF3 building block •Polymerization catalyst •(Trans-)Esterification promoter •Amino acid protection group cleavage (e.g. DIBOC) •Non-aqueous solvent •Hydration of olefins

The number of HPAPI (High Potency Active Pharmaceutical Ingredient) has been continuously increasing over the past view years. At the same time, the manufacturing industry wants more flexibility in production to respond faster and more accurately to needs and changing demand. The complete IBC cleaning and drying solution for substances with high hazard classification up to OEB 5 for pharmaceutical industries is at the end of all process steps in pharmaceutical solids production and meets this requirement including full validation. Validated interior cleaning adapted to space and product Technical description suitable for high containment containment Valve system with Split Butterfly Valves single-stage washing principle, no water circulation to avoid cross-contamination hydrokinetic head for cleaning (container) inner surfaces hydrokinetic head for cleaning bottom valves recipe controlled system with automatic controls, sampling, batch reporting and security access drying with...

Without the pad printing process, the production of everyday objects such as decorated light alloy wheels, or even vital items such as insulin pens would not be easily possible. In doing so, TAMPOPRINT develops and works on process printing solutions across industry boundaries. Thus, there is no such thing as the typical TAMPOPRINT customer or the typical application. Rather, the fields of application are characterized by their diversity, their complexity and their individual characteristics. They range from the simpler printing of toys such as model trains, to the labeling of household appliances and beverage bottles, to highly complex processes such as the micrometer-accurate labeling of medical products, e.g. insulin pens and laboratory tubes. Even the particularly challenging direct application of active pharmaceutical ingredients onto a carrier material, such as in nicotine patches, can be implemented thanks to the TAMPOPRINT solutions.

The complex nature of the active ingredients in pharmaceutical products requires grinding equipment adapted for the extra care and attention necessary. All our equipment is designed for easycleaning and steamsterilisation.

The comminution or desagglomeration of active pharmaceutical ingredients (API) is called micronization and brings about several advantages. The increase of the particle surface caused by the comminution results in a considerably better dissolution rate and bioavailability of the agents and therefore the APIs act faster. Due to the increased bioavailability a lower amount of APIs is required which in turn leads to a more cost-efficient product with less risks and side effects for the patient. Based on comprehensive experience with the production of GMP-compliant pharmaceutical products, all sizes of NETZSCH DeltaVita® machines ranging from small laboratory- to production-size machines excel by the following specific features: •All product wetted parts are designed and manufactured according to the latest GMP standards •Material, production and calibration certificates are supplied together with the machine •Optional cleaning in … ** click to know more **