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We offer you the following services: - Regulatory Advice - REACH Registration - Preparation of Registration Dossiers - Read Across - IUCLID - Robust Study Summaries - Chemical Safety Report / CSR - Toxicological Expertise - Optimal Test Strategy Development - REACH Testing: Tests and Studies acc. GLP - REACH Study Monitoring - SVHC Screening - Risk Assessment - REACh Compliance Service / REACh Auditing Service - REACH Material Safety Data Sheets We would also be happy to be your REACH service provider, who reliably looks after your REACH projects, just as we already do for many other satisfied customers. For more information please contact INVITRO-CONNECT GmbH. Fast Project Execution: personal - competent - reliable --> contact@invitro-connect.com REACH Service - All REACH laboratory tests - Phys-Chem / Tox / in vitro tests / Genotox / Ecotox, etc. - More than 80 test laboratories - Study monitoring, Regulatory Service, IUCLID 6, CSR etc.

Professional image solutions are housed at AED Display Large venue projectors (including lenses and screens), LED screens, displays, monitors, media servers, and controllers, processors, switchers, mixers and last-generation professional cameras, including accessoires, can be hired or purchased by audiovisual rental and installation companies.

The epidermal barrier undergoes continuous renewal through a process called homeostasis, during which epidermal stem cells provide new keratinocytes that will go through a complex maturation process to replace corneocytes that are constantly lost during the desquamation and tissue turnover. Active ingredients with an effect on the epidermal homeostasis can be screened by monitoring tissue cohesion markers and differentiation markers. The biological endpoints are assessed by immunofluorescence of proteins involved in: Tight junctions (claudins, occluding, ZO-1) Corneo-desmosomes (corneodesmosin, desmogleins) Cornified envelope (involucrin, loricrin, filaggrin) The effects of a test item on the skin barrier can also be evaluated by measuring: Resistance Trans-epidermal electric resistance (TEER) Diffusion Skin diffusion of chromogenic dyes StratiCELL has also designed a TaqMan low density qPCR array to study the expression levels of 96 target genes carefully selected.