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The VERTEX FTIR research spectrometer productline is the culmination of everything Bruker has pioneered and developed in over 40 years. The VERTEX Series is built on a fully upgradeable optics platform that is designed with the utmost flexibility in mind. VERTEX spectrometers share a wide range of features, including an intelligent network for automation, Automatic Component Recognition (ACR), the Plug & Play Ethernet connection and Automatic Accessory Recognition (AAR). VERTEX 70v Bruker's VERTEX 70v FTIR Spectrometer is based on the well-known RockSolid™ interferometer and the ideal entry level systems for Advanced Research applications. The vacuum optics bench provides class leading specifications. VERTEX 80/80v The high-end VERTEX 80 and the VERTEX 80v vacuum FTIR spectrometers are based on the actively aligned UltraScan™ interferometer, which provides PEAK spectral resolution and highest scanning speed.

The LUMOS II offers outstanding visual and spectral data quality with full automation of all measurement modes: transmission, reflection and ATR. For FTIR beginners and experts alike, the LUMOS II is the best solution for infrared microscopy. Bruker's exclusive Focal Plane Array (FPA) detector technology allows you to experience detailed imaging at the maximum speed. This allows you to take full advantage of the vast possibilities offered by FT-IR microscopy. The OPUS IR software provides you with assistance whenever you need it and allows you to glide effortlessly through measurement, evaluation and reporting. Your advantages: • Extremely fast FT-IR imaging (FPA) • High spectral quality and resolution • Brilliant visual images and huge field of view • Fully automated FT-IR microscope • Integrated, piezo-controlled ATR crystal • Software supported measurement and evaluation • Automatic measurement in transmission, reflection and ATR

VERTEX 80v is the gold standard of R&D FTIR spectroscopy regarding performance, sensitivity and flexibility. With the unique verTera THz extension the VERTEX 80v is now the first and only all-in-one system combining the advantages of FTIR and continuous wave THz spectroscopy, gaining access to an extremely broad spectral range and exciting new possibilities. Unique features: • Hybrid spectrometer FTIR/cw THz spectrometer with spectral range up to 3-50000 cm-1 • No cryogenically cooled components required • Unique effective spectral resolution < 0.0007 cm-1 • Unmatched THz performance due to vacuum beam path and optimized THz data processing • Same sample compartment & accessories applicable for FTIR and cw THz • FTIR and THz mode controlled via OPUS software with full data compatibility

The FTIR spectrometer ALPHA II combines outstanding quality with a small footprint and sets a benchmark in terms of user convenience. With the integrated panel PC and the touch-based operation, FTIR spectroscopy has never been easier. The ALPHA II features a new way to operate an FTIR spectrometer. With the integrated panel PC and the dedicated OPUS-TOUCH user interface it takes only three touches for measurement, evaluation and report generation. OPUS-TOUCH is very intuitive and guides you conveniently through the measurement and evaluation process. Alternatively the ALPHA II can also be operated with an external PC.

The award winning MATRIX-F II FT-NIR spectrometer allows the direct measurement in process reactors and pipelines, leading to a better understanding and control of the process. Accurate in-line results in seconds Multiple components per measurement Non-destructive analysis Optional built-in 6-port multiplexer Direct method transfer Rugged design Ethernet connectivity and industry standard communication protocols

10 cm optical path length for the identification and quantification of high gas concentrations Volume inside the gas cell is 25 ml only PTFE coating of the gas cell enables the measurement even of corrosive gases Accounts for variable pressure and temperature of the gas by sensors The MATRIX-MG01 features a gas cell with 10 cm optical path length and is especially well suited for the quantification of gas compounds with very high concentration. The cell has a volume of 25 ml only to enable a fast gas exchange with minimum gas consumption. Its PTFE coating and ZnSe windows ensure a maximum corrosive protection. The MATRIX-MG01 is equipped with temperature and pressure sensors and their measurement values are automatically read out and considered within the control software OPUS GA.

MATRIX-MF is a rugged and a compact spectrometer that can be fiber optically coupled to measure chemical reactions in laboratory and/or process environments. Bruker's MATRIX-MF FTIR spectrometer expands the proven MATRIX series product line utilizing the information rich mid-IR region for use in both laboratory and process environments. The MATRIX-MF is a process ready FTIR spectrometer that is ideal for real-time monitoring and analysis of chemical and biological reactions.

The SENTERRA II defines a new level of spectroscopic performance and user friendliness in the class of compact Raman microscopes. SENTERRA II is designed to deliver excellent sensitivity combined with high spectral and imaging performance. Therefore the SENTERRA II is a powerful platform for advanced research applications. Due to its high degree of automation, compact size and efficient workflow the SENTERRA II is likewise an ideal tool for solving real world tasks in the quality control laboratory. Its unprecedented permanent stability of the wavenumber axis guarantees precise and accurate results at every time. The SENTERRA II is THE Raman microscope for both, the multi-user environment with high daily throughput and for the lab working at the forefront of scientific research.

The HYPERION II microscope combines FT-IR and infrared laser imaging (ILIM) microscopy in a single instrument for the first time. It offers all three measurement modes: transmission, reflection and ATR. Now, users have the unique opportunity to use an IR microscope that offers both, the reliability and precision of FT-IR and the tremendous speed advantage of IR laser imaging, all in one.

FTIR Excellence for Industry, R&D and Science: INVENIO INVENIO is the definitive spectroscopic solution for routine FTIR analysis as well as research and development. It is all you need and so much more: innovative technologies, intelligent design and its new beam path contribute to an unrivalled user experience. Your advantage: •Outstanding signal-to-noise ratio •Broad spectral range (FIR, MIR, NIR and VIS/UV) •Touch-PC with dedicated software for enhanced productivity •MultiTect™: Up to seven automated and software controlled internal detectors •Transit™: parallel availability of two experimental setups •RockSolid™: reliable, well-proven and precise •CenterGlow™ IR source: optimized light flux and durability •Bruker FM: MIR and FIR spectra in one go •Upgradability: retrofit spectral range extensions or time resolved measurements •Multiple beam inputs and outputs •Compact footprint optimized for laboratory benches

Thermogravimetric analysis (TG) follows changes in mass of the sample as a function of temperature and/or time. TG gives characteristic information about the composition of the measured sample, in particular the amounts of the various components and their thermal behavior. In addition, further measurements are possible such as kinetic analysis of thermal decomposition. The identification of gases released directly from the sample or during thermal treatment cannot be performed just by thermal analysis, but coupling a spectroscopic method such as Fourier-Transform-Infrared (FTIR) spectroscopy is an excellent solution. IR spectroscopy is a classical technique, which depends upon the interaction of infrared radiation with the vibrating dipole moments of molecules. It gives, with the exception of homonuclear diatomics and noble gases, a characteristic spectrum for each substance.

The external accessory PMA 50 has been specially developed for Polarization Modulation measurements. It can be adapted to Bruker TENSOR, INVENIO and VERTEX FTIR spectrometers. All optic and electronic components in the PMA 50 module are optimized for the Polarization Modulation. Both linear dichroitic measurement techniques like PM-IRRAS and circular dichroitic experiments like VCD spectroscopy can be realized using this dedicated system. The core of the Polarization Modulation technique is the Photoelastic Modulator (PEM) with a nominal modulation frequency of 42 kHz. With the help of the parallel 24-bit dual-channel data acquisition technology the sum and the difference signals can be collected simultaneously with highest sensitivity. The PMA 50 module exhibits short beam path, and therefore provides optimal S/N ratio and stability.

The CONFOCHECK is a dedicated FTIR system for the investigation of proteins in water. Its specific configuration facilitates a fast data acquisition (ca. 30 sec. per sample) with a high sample throughput controlled by an extremely user-friendly software interface. FTIR Protein Applications Protein quantification Detection of conformational changes Protein dynamics (temperature induced conformational changes) Monitoring of conformational changes during protein aggregation, precipitation and crystallization Determination of the secondary structure Quantification of all kind of solutes in aqueous samples (buffers, excipients, detergents) Typical Applications in Pharma: Pre-formulation and formulation development: Analysis of the influence of the formulation on protein stability Stability studies (stress tests): Influence of pH, temperature, mutation, etc. on the protein stability

SiBrickScan (SBS) is a dedicated at-line system for the FTIR quantification of interstitial Oxygen in complete Silicon ingots, resulting in a concentration profile along the longitudinal axis. Accessing this information without sawing wafers or test samples is a major and cost saving advantage. Get Valuable Information to Check and Optimize Product Quality Knowing the Oxygen gradient of Si ingots enables important conclusions helping e.g. to control and optimize the Silicon crystallization process or to identify batches of bad raw material. Therefore SBS will help to save costs by optimizing product quality and reducing the amount of defective wafers. The random sampling of individual ingots does strongly reduce sample preparation efforts and provides relevant information much earlier.

The Bruker Optics` Cryogenic Silicon Analysis System (CryoSAS) is a dedicated all-in-one system for the low temperature (<15K) impurity analysis of Silicon. CryoSAS is optimized for operation in the industrial environment. CryoSAS combines Bruker's high performance FTIR spectrometers with built-in, closed-cycle cryo-cooling technique that does not require any liquid Helium. All CryoSAS components are state-of-the-art, yet utilize proven technologies to accomplish a difficult analysis in the demanding silicon production environment. CryoSAS can be operated at a high level of automation including accurate reporting of the analysis results.

The IFS 125HR is the ultimate instrument for the high resolution IR spectroscopy Outstanding results in your laboratory In absorption or emission mode, the IFS 125HR can resolve highly complex spectra into discrete lines for recognition and spectral assignment. Outstanding resolution across the entire spectrum Resolved linewidths of < 0.0009cm -1 Broad spectral range: from 5cm -1 in the far-IR to >50,000cm -1 in the UV Double-sided interferogram acquisition (option) Symmetric line shapes - due to high precision optics Easy range change - every experiment can access different sources and detectors without breaking vacuum. A total of 4 sources and 6 detectors can be accessed through each of two different sample compartments

Application areas: - health care - drug discovery - pharmacy - environmental monitoring - forensic science - homeland security Technical performance: - patented design is a combination of a multifunctional sample introduction and ionization system, drift tube ion mobility spectrometer and sector TOF mass spectrometer with orthogonal acceleration - Multifunction sample introduction and ionization system works with both integrated ion sources and external available engineering solutions. Integrated ionization platform allows to use electrospray (ESI), atmosphere pressure chemical ionization (APCI), atmosphere pressure photoionization (APPI) - high resolution ion mobility spectrometer provides maximum selectivity compared to existing commercial instruments Main advantages: - allows to reach better sensitivity than approaches based on orthogonal acceleration reflectron TOF analyzers - allows to analyze gases and liquids much faster than liquid chromatography/mass spectrometry

IROS 03 Fourier infrared spectrometer is designed to record absorption spectra of solid, liquid, and gaseous substances in the near and medium IR region (including drugs, varnishes and paints, oil products, pharmaceuticals, polymer films, and fibers) with their subsequent identification, as well as for qualitative and quantitative analysis of mixtures containing several components. Main Advantages: - Unique misalignment-free, humidity and temperature change resistant Double Cat’s Eye interferometer - Sealed drainable optical unit - The ability to expand the spectral range using additional radiation sources, detectors and beam splitters - Three ports for connecting external devices - Great variety of extension modules IROS 03 FTIR Spectrometer can be equipped with a large number of extension modules. It makes possible to use IROS 03 for different common and specific applications.

IROS 05i is a special FTIR spectrometer designed for work in harsh conditions. This model allows solving a wide range of industrial problems, including process control, with the possibility of online (in situ) monitoring of industrial processes (in reactors or pipelines) both for laboratories and industry facilities. Features: - Completely tight metal case - Ports for connecting external cooler and purging with inert gases to protect and stabilize the optical unit in difficult environmental conditions - Module for connecting fiber optic probes (up to 2 simultaneously) Advantages: - Ability to connect 2 probes, allows working with the device in 2-channel mode, monitoring simultaneously processes taking place in 2 different reaction environments - Control software allows setting flexible routines with continuous analysis and evaluation of data obtained in real-time - Wide range of probes designed for use in corrosive environments, at high pressures and temperature, among others

IROS 05 FTIR spectrometer is designed to provide a wide range of sample measurement techniques in the most challenging environments, from the scientific laboratory to the industrial production line. Compact size, reasonable price, a unique set of accessories and high performance – these advantages of IROS 05 spectrometer allow it to fit most of research and field tasks as a midlevel spectrometer for academic and industrial applications. Features: - A wide array of functions due to various attached modules and detectors - Capability of additional external devices connection for IR spectrum registration - Stability to temperature fluctuation and vibration due to unique patented interferometer design - Humidity resistance because of ZnSe optics - Spectrum recording control buttons on device case for fast routine operations - Compact and light-weight IROS 05 can be combined with wide-range IR microscope IR M series and FiPOS ATR fiber probes.

GAOS MS mass spectrometers provide fast, accurate, and comprehensive gas analysis in real-time. Operational characteristics: - Modular configuration, quick replacement of units for maintenance and repair; - Protective performance according to customer requirements; - Continuous operation 24 hours for 6 to 12 months without servicing the vacuum system; - Automatic algorithm of work with functions of diagnostics, adjustment, calibration and operational control of measurement accuracy. Depending on analytical applications, GAOS MS process mass spectrometers are equipped with various modifications of the sample preparation system. Continuous sampling of the gas probe under conditions: - Temperature up to 1200 °C; - Dust content up to 30 g/m3; - Pressure (10-3÷3) bar; - Presence of condensate, aggressive gases;