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From traditional medicine, Triptolide is widely used in east Asia for the treatment of immune-inflammatory diseases – psoriasis and asthma. It can lessen the effects of other inflammatory responses.
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Squalene has gained its major attraction thanks to the COVID-19 vaccine as it is used as an adjuvant. The primary purpose of squalene in vaccines is its increasing immune response to the vaccine itself promoting better protection.
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Nootkatone is a natural sesquiterpene. It is one of the main constituents of the grapefruit aroma and, hence, can be isolated from them. However, it can also be identified significantly in Alaska yellow cedar trees and vetiver grass.
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Synonyms: all-trans-Lycopene, E 160d, Lyco Vit, Lyconat, Lycopene, Lycored, Redivivo, Solanorubin
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Lutein is a natural compound in the carotenoid compound class. It is a xanthophyll compound (yellow pigment) and can be isolated in large amounts from green and yellow plants like kale, spinach, yellow carrot, and others.
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Lathyrol and its derivatives are highly studied for their anti-cancer properties. It has been exhibited to modulate cancer cell drug resistance by altering drug-reflux transporters and more.
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Ingenol and its ester derivative have been used to treat various skin problems, Ingenol mebutate has been approved by both US and EU drug administrations for the topical treatment of actinic keratosis by the induction of cell death. However, its use has been withdrawn from the EU.
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Forskolin has been extensively studied as a weight-regulating supplement. Few studies have shown greater weight loss for subjects using Forskolin compared to others while maintaining higher testosterone levels.
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Carnosic acid is primarily used as an antioxidant for food and non-food purposes. It can react with reactive oxygen species, hence, protecting the skin, cells, and sensitive biochemicals.
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Synonyms: Astaxanthin, Natupink, BioAstin, Carophyll Pink, Lucantin Pink, trans-Astaxanthin
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Synonyms: Arteannuic acid, Arteannuinic acid, Artemisic acid, Artemisininic acid, Qing Hao acid
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Medicinal chemists have identified that bakuchiol can interact with the same enzymes as retinol. It can modulate the receptors of retinoic acid, upregulate collagen and extracellular matrix synthesis enzymes, therefore, it has gained quite the attention from cosmetics industries. However, bakuchiol has been screened and showed good results for other biological effects like
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Oleanolic acid, like other triterpenoids, has gained attention due to its similarity with various steroids. Therefore, it has been extensively studied for its activity against cancer by identifying multiple cellular pathways, for example, induction of apoptosis
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Maslinic acid and its derivatives have been widely studied for their anti-cancer properties. It has shown the ability to inhibit cancer formation and growth by various cellular pathways like apoptosis, induction of oxidative stress, and more.
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Synonyms: Monogynol B, (+)-Lupeol, Clerodol, Fagarasterol, Lupenol, β-Viscol
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Hederagenin is a natural compound in the triterpenoid compound class. It can be isolated from various sources in nature like common ivy Hedera helix and quinoa Chenopodium quinoa.
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Cycloastragenol has been extensively studied for its properties on telomerase activation. Telomeres are a part of chromosomes scientists believe are responsible for cell aging and cycloastragenol is believed to probably inhibit maturation of cells.
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Celastrol is a natural compound in the triterpenoid compound class. It can be isolated from the roots of the Thunder god vine Triperygium wilfordii and Regel’s threewignut Tripterygium regelii.
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Like the extracts of Gotu Kola, Asiaticoside’s main application is in cosmetics and skin treatment. This compound has shown the ability to promote skin healing and improve the conditions of the diseases like leprosy, lupus, varicose ulcer, eczema, and more.
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Ammonium Glycyrrhizate is a natural compound in the saponin-triterpene glycoside compound class. It is an ammonium salt of widely studied Glycyrrhizic acid. It possesses a sweet taste and is the main component of liqourice Glycyrrhiza glabra root.
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Synonyms: (+)-Dipsacobioside, Akebia saponin PD, Akeboside Stc, Cephalaroside C, Dipsacoside A, Dipsacus saponin L, Glycoside L-E1, Hederoside C, Helixin, Kalopanaxsaponin A, Koronaroside A, Nepalin 2, Prosapogenin CP3b, Pulchinenoside BD, Pulsatilla saponin A, Sapindoside A, Tauroside E
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Thiamine monophosphate chloride dihydrate is a natural compound and a phosphorylated version of thiamine – an essential vitamin B1. It can be obtained from various dietary sources like meat, whole grain, and legumes.
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