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Squalene has gained its major attraction thanks to the COVID-19 vaccine as it is used as an adjuvant. The primary purpose of squalene in vaccines is its increasing immune response to the vaccine itself promoting better protection.
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Synonyms: all-trans-Lycopene, E 160d, Lyco Vit, Lyconat, Lycopene, Lycored, Redivivo, Solanorubin
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Ingenol and its ester derivative have been used to treat various skin problems, Ingenol mebutate has been approved by both US and EU drug administrations for the topical treatment of actinic keratosis by the induction of cell death. However, its use has been withdrawn from the EU.
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Forskolin has been extensively studied as a weight-regulating supplement. Few studies have shown greater weight loss for subjects using Forskolin compared to others while maintaining higher testosterone levels.
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Synonyms: Alaxin, Artenimol, Cotecxin, Cotexin, Dihydroartemisinine, Dihydroqinghaosu, Dynamax, Salaxin, Santecxin
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Synonyms: Adelir, Bio-Quinon, Aqua Q10, Coenzyme Qter, Cudesan, Ensorb, Kudesan, Neuquinon, Ubiquinone 10, Ubiquinone Q10, Vitamin Q
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Carvacrol is a natural compound in the monoterpenoid compound class. It is one of the main substituents in the essential oils of oregano Origanum vulgare, hence it has a pungent characteristic smell of that plant. It can also be identified in other plants as well like thyme, pepperwort, wild bergamot, and more.
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Synonyms: Astaxanthin, Natupink, BioAstin, Carophyll Pink, Lucantin Pink, trans-Astaxanthin
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Artemisinin is a natural compound in the sesquiterpene lactone compound class. In nature, it has been isolated from sweet wormwood species like Artemisia annua and Artemisia apiacea Hance.
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Synonyms: Arteannuic acid, Arteannuinic acid, Artemisic acid, Artemisininic acid, Qing Hao acid
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Medicinal chemists have identified that bakuchiol can interact with the same enzymes as retinol. It can modulate the receptors of retinoic acid, upregulate collagen and extracellular matrix synthesis enzymes, therefore, it has gained quite the attention from cosmetics industries. However, bakuchiol has been screened and showed good results for other biological effects like
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Glycyrrhetinic acid is a natural compound triterpenoid compound class. Together with its glycosilated counterpart Glycyrrhizic acid it can mainly be isolated from liqorice Glycyrrhiza glabra root.
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Oleanolic acid, like other triterpenoids, has gained attention due to its similarity with various steroids. Therefore, it has been extensively studied for its activity against cancer by identifying multiple cellular pathways, for example, induction of apoptosis
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Most commonly it is found in various fruits and vegetables like apples, several types of berries, and much more. However, the abundance in plant-based foods and solubility of Ursolic acid is quite low, ursolic acid powder supplements are highly popular.
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Maslinic acid and its derivatives have been widely studied for their anti-cancer properties. It has shown the ability to inhibit cancer formation and growth by various cellular pathways like apoptosis, induction of oxidative stress, and more.
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Synonyms: Monogynol B, (+)-Lupeol, Clerodol, Fagarasterol, Lupenol, β-Viscol
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Hederagenin is a natural compound in the triterpenoid compound class. It can be isolated from various sources in nature like common ivy Hedera helix and quinoa Chenopodium quinoa.
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Cycloastragenol has been extensively studied for its properties on telomerase activation. Telomeres are a part of chromosomes scientists believe are responsible for cell aging and cycloastragenol is believed to probably inhibit maturation of cells.
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Celastrol is a natural compound in the triterpenoid compound class. It can be isolated from the roots of the Thunder god vine Triperygium wilfordii and Regel’s threewignut Tripterygium regelii.
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Like the extracts of Gotu Kola, Asiaticoside’s main application is in cosmetics and skin treatment. This compound has shown the ability to promote skin healing and improve the conditions of the diseases like leprosy, lupus, varicose ulcer, eczema, and more.
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Ammonium Glycyrrhizate is a natural compound in the saponin-triterpene glycoside compound class. It is an ammonium salt of widely studied Glycyrrhizic acid. It possesses a sweet taste and is the main component of liqourice Glycyrrhiza glabra root.
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Synonyms: (+)-Dipsacobioside, Akebia saponin PD, Akeboside Stc, Cephalaroside C, Dipsacoside A, Dipsacus saponin L, Glycoside L-E1, Hederoside C, Helixin, Kalopanaxsaponin A, Koronaroside A, Nepalin 2, Prosapogenin CP3b, Pulchinenoside BD, Pulsatilla saponin A, Sapindoside A, Tauroside E
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Thiamine monophosphate chloride dihydrate is a natural compound and a phosphorylated version of thiamine – an essential vitamin B1. It can be obtained from various dietary sources like meat, whole grain, and legumes.
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