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What can Surgiderm 18 be used for? Finewrinkle lines Laughter lines Smoker lines Perioral lines What’s comes with box? (2 x 0.8ml syringes) SideEffects of Surgiderm 18? Minor swelling, bruising and redness may occur right after the procedure as well as the irritation of the skin. Also the patient may feel slight pain and can see minor lumps at the area of injection. Some other reported reactions include from this treatment include hypersensitivity to HA. Reversible coloring is very rare but has also been reported as one side effect too. All side effects are usually resolved in less than one week. Patients who are not recommended Surgiderm 18 XP? Women in labor (who are pregnant) or lactating women should not use Surgiderm, as well as anyone who is prone to develop skin scarring reactions.