Aqueous solution - Import export

The CONFOCHECK is a dedicated FTIR system for the investigation of proteins in water. Its specific configuration facilitates a fast data acquisition (ca. 30 sec. per sample) with a high sample throughput controlled by an extremely user-friendly software interface. FTIR Protein Applications Protein quantification Detection of conformational changes Protein dynamics (temperature induced conformational changes) Monitoring of conformational changes during protein aggregation, precipitation and crystallization Determination of the secondary structure Quantification of all kind of solutes in aqueous samples (buffers, excipients, detergents) Typical Applications in Pharma: Pre-formulation and formulation development: Analysis of the influence of the formulation on protein stability Stability studies (stress tests): Influence of pH, temperature, mutation, etc. on the protein stability