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Crocin , one of the active components of saffron has showed strong antioxidant effects. Saffron and its Crocins are potential anti-cancer and also a hypolipidemic and antioxidant agent, protects brain against excessive oxidative stress, protective on ischemic heart, useful in alleviation of cognitive deficits, possesses significant anti-proliferation effects on human prostate and colorectal cancer cells, aphrodisiac activity, immunomodulatory, beneficial in diabetic neuropathy treatment, effects glucose uptake and insulin sensitivity and too many other activities. Crocin showed various pharmacological effects on the nervous system such as antianxiety activity, antidepressant effects, aphrodisiac properties, learning and memoryenhancement.1 Alzheimer’s disease (AD) is the most common form of dementia, in which the death of brain cells causes memory loss and cognitive decline. Several factors are thought to play roles in the development and course of AD.
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