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The kit is used for in vitro qualitative detection of monkeypox virus DNA in blood, wound or pus samples from suspected monkeypox patients. It is for professional use only. Not for self-testing.
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NMN (Nicotinamide mononucleotide): The full name is "β-nicotinamide mononucleotide", which is a naturally occurring biologically active nucleotide. NMN has two irregular forms, α and β; β isomer is the active form of NMN with a molecular weight of 334.221g/mol. Because nicotinamide belongs to vitamin B3, NMN belongs to the category of vitamin B derivatives. It is widely involved in many biochemical reactions of the human body and is closely related to immunity and metabolism. Molecular structure NMN (full name β-nicotinamide mononucleotide)-"C11H15N2O8P", a molecule that naturally exists in all life forms. At the molecular level, it is ribonucleic acid, the basic structural unit of nucleic acid RNA. Structurally, the molecule consists of nicotinamide, ribose and phosphate groups. NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered to be a key component to increase the level of NAD+ in cells.
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It is used for rapid inactivation and release of virus in samples, and the preservation of nucleic acid. It is suitable for collection, transportation and preservation of sample, etc. This kit consists of sampling swabs and preservation vials (including lysis solution and nucleic acid preservation solution). The protein denaturant contained in the kit can denature the virus shell, rapidly crack and inactivate the virus, and release nucleic acid at the same time, thus preventing the secondary transmission of the virus to the medical staff during the sampling process. Meanwhile, buffer components (Tris-HCl), EDTA contained in the kit can effectively inhibit the activity of nuclease, maintain the stability of nucleic acid, effectively protect nucleic acid and achieve the effect of stable preservation of nucleic acid. The obtained nucleic acid can be directly used in RT-PCR reaction. This kit is used for collecting, transporting and storing samples..
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