Inflammations - Import export

Using functional and standardised 2D or 3D living skin models, the bioassays performed by StratiCELL are very powerful tools for assessing the efficacy and mechanisms of action of products aimed at reducing skin inflammation and increasing skin barrier resilience. Examples of assays performed at StratiCELL: Barrier resilience and biomarkers NFkB translocation/activation Morphological alterations (such as spongiosis) Cytokines and chemokines release (IL1a, IL-1ß, IL-6, IL-8, etc.)

StratiCELL has developed a range of assays to study the protective effects of compounds against acute inflammation induced by specific triggers such as UV radiation, phorbol myristate acetate, bacterial lipopolysaccharides, etc. Examples of assays performed at StratiCELL: Cytokines release (IL-1 α/ß, TNFα, IL-6, IL-8, PGE2, …) NFκB translocation